Disclosure obligations of major shareholders
According to the Transparency Directive implemented in Denmark as of 1 June 2007
shareholders are obliged to notify both Novo Nordisk and the Danish Financial Supervisory Authority where the proportion of the voting rights or the nominal value held by the shareholder as a result of the acquisition or disposal reaches, exceeds or falls below the thresholds of 5%, 10%, 15%, 20%, 25%, 1/3, 50%, 2/3 and 90%. The voting rights shall be calculated on the basis of all the shares to which voting rights are attached even if the exercise thereof is suspended.
The notification shall as a minimum include the following information:
(a) the resulting situation in terms of voting rights;
(b) the chain of controlled undertakings through which voting rights are effectively held, if applicable;
(c) the date on which the threshold was reached or crossed; and
(d) the identity of the shareholder.
The notification shall be effected as soon as possible.
The notification to Novo Nordisk shall be made by post or fax to the Head of Investor Relations. The notification to the Danish Financial Supervisory Authority shall be made electronically and using digital signature via the Danish Financial Supervisory Authority webpage.



